Hydroxyzine product monograph

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About Hydroxyzine

About Hydroxyzine

Hydroxyzine is a medication that is used to treat various conditions, including anxiety and itching. It belongs to a class of drugs called antihistamines, which work by blocking the effects of histamine in the body.

How Does Hydroxyzine Work?

Hydroxyzine works by blocking the H1 receptors in the body, which reduces or prevents the symptoms caused by histamine release. Histamine is a natural substance produced by the body in response to an allergen. It is responsible for causing symptoms such as itching, sneezing, and watery eyes.

By blocking the H1 receptors, Hydroxyzine effectively reduces these symptoms. It also has sedative properties, which can help to reduce anxiety and promote relaxation.

Indications for Use

Hydroxyzine is indicated for various conditions, including:

  • Generalized anxiety disorder
  • Allergic reactions
  • Itching due to allergies or hives
  • Sedation

It may be used for other purposes not listed here. It is important to follow the instructions provided by your healthcare professional for proper use and dosage.

Before taking Hydroxyzine, it is important to inform your healthcare professional of any other medications you are taking, as well as any medical conditions you may have. They will be able to determine if Hydroxyzine is right for you and provide appropriate guidance.

Note: This post is for informational purposes only and is not a substitute for medical advice. Consult your healthcare professional before starting any new medication.

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Indications for Use

Hydroxyzine is indicated for the symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. It is also useful in managing pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses.

Dosage and Administration

Hydroxyzine should be taken exactly as prescribed by your healthcare provider. It is important to follow the recommended dosage and administration instructions to ensure safe and effective use.

The dosage of Hydroxyzine may vary depending on the specific condition being treated, the severity of symptoms, and individual patient factors. Your healthcare provider will determine the appropriate dosage for you.

Hydroxyzine is available in various forms, including tablets, capsules, and syrup. It can be taken with or without food. Make sure to read the product label and follow the directions provided.

If you are using the syrup form of Hydroxyzine, it is important to measure the liquid accurately using a special measuring device. Do not use a household spoon, as it may not provide the correct dose.

Do not exceed the recommended dosage of Hydroxyzine without consulting your healthcare provider. Taking more than the prescribed amount can increase the risk of side effects.

If you miss a dose of Hydroxyzine, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

It is important to continue taking Hydroxyzine for the full duration of treatment, even if you start to feel better. Stopping the medication prematurely may result in a return of symptoms.

If you have any questions or concerns about the dosage or administration of Hydroxyzine, consult your healthcare provider for further guidance.

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Hydroxyzine is contraindicated in individuals with a known hypersensitivity to hydroxyzine or any of its components. It should not be used in patients who have a history of hypersensitivity reactions, including anaphylaxis, to any antihistamines or other related drugs.

Patients with narrow-angle glaucoma should not take hydroxyzine, as it may increase intraocular pressure.

Hydroxyzine is contraindicated in patients with a history of QT prolongation, since it may further prolong the QT interval and increase the risk of life-threatening arrhythmias, such as torsades de pointes.

Concurrent use of hydroxyzine with monoamine oxidase inhibitors (MAOIs) is contraindicated, as it may result in enhanced central nervous system depression and hypertensive reactions.

Hydroxyzine is contraindicated in patients with a history of severe cardiovascular disease, including heart block, congestive heart failure, and ventricular arrhythmias.

Combining hydroxyzine with alcohol or other central nervous system depressants should also be avoided, as it may potentiate the sedative effects and increase the risk of respiratory depression.

Patients with porphyria, a rare genetic disorder affecting the production of heme, should not take hydroxyzine, as it may trigger acute attacks.

During pregnancy and lactation, the use of hydroxyzine should be avoided, unless the potential benefits outweigh the risks.

It is important for healthcare professionals to review the patient’s medical history and current medications before prescribing hydroxyzine to identify potential contraindications and minimize the risk of adverse effects.

Warnings and Precautions

Warnings and Precautions

Before taking Hydroxyzine, it is important to be aware of the following warnings and precautions:

Allergic Reactions

Some individuals may experience allergic reactions to Hydroxyzine. If you have a known allergy to Hydroxyzine or any of its ingredients, do not take this medication. Seek immediate medical attention if you develop symptoms of an allergic reaction, such as difficulty breathing, rash, hives, or swelling.

Central Nervous System Depression

Hydroxyzine may cause central nervous system depression, which can impair your thinking or reactions. Avoid activities that require mental alertness, such as driving or operating machinery, until you know how this medication affects you.

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Interactions with Other Medications

Tell your doctor or pharmacist about all the medications you are currently taking, including prescription and over-the-counter drugs, as well as any herbal supplements. Hydroxyzine can interact with certain medications, such as sedatives, tranquilizers, or other antihistamines, leading to increased drowsiness or other side effects.

It is important to inform your healthcare provider if you are taking any other medications to avoid potential drug interactions.

Pregnancy and Breastfeeding

Hydroxyzine should be used with caution during pregnancy, especially during the first trimester. It is important to discuss the potential risks and benefits with your healthcare provider before taking this medication if you are pregnant or planning to become pregnant.

Hydroxyzine may pass into breast milk and could harm a nursing baby. Consult your healthcare provider before using Hydroxyzine while breastfeeding.

Elderly and Debilitated Patients

Elderly patients and those with debilitating conditions may be more sensitive to the effects of Hydroxyzine. Lower doses or close monitoring may be necessary for this population.

Medical Conditions

Inform your healthcare provider about any existing medical conditions you have, such as glaucoma, urinary retention, heart problems, liver disease, or kidney disease. Hydroxyzine may worsen these conditions or interact with other medications used to treat them.

Follow all warnings and precautions provided by your healthcare provider, and take Hydroxyzine only as directed. Do not exceed the recommended dose or take this medication for longer than prescribed.

If you experience any unexpected or concerning side effects while taking Hydroxyzine, contact your healthcare provider immediately.

Adverse Reactions

While Hydroxyzine is generally well-tolerated, some patients may experience adverse reactions. It is important to be aware of these potential side effects before starting treatment.

Common side effects:

  • Nausea and vomiting
  • Dry mouth
  • Drowsiness
  • Headache
  • Dizziness

Less common side effects:

  • Blurred vision
  • Confusion
  • Difficulty urinating
  • Constipation
  • Increased heart rate

These are not all the possible side effects of Hydroxyzine. If you notice any other unusual or severe reactions, it is important to contact your healthcare provider.

Please note that this is not a complete list of side effects. Consult the Hydroxyzine product monograph for more information.