Hydroxyzine vs xyzal

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Find out which allergy medication is right for you!

Are you struggling with allergies and searching for the best medication to relieve your symptoms? Look no further than Hydroxyzine and Xyzal. In the battle of the allergy relievers, these two medications are fighting for your attention.

Hydroxyzine is a fast-acting antihistamine that effectively reduces allergy symptoms, such as itching, sneezing, and watery eyes. It works by blocking the histamine receptors, providing you with instant relief.

Xyzal is a long-lasting antihistamine that provides 24-hour relief from allergy symptoms. With just one daily dose, you can free yourself from the hassle of taking multiple tablets throughout the day.

Both Hydroxyzine and Xyzal are proven to be highly effective in treating allergies, but the choice between them depends on your specific needs. Whether you need immediate relief or long-lasting protection, we have the right allergy medication for you.

Consult your healthcare provider to determine which medication is best for you!

What is Xyzal?

Xyzal is an antihistamine medication that is commonly used to treat allergy symptoms such as sneezing, runny nose, watery eyes, and itching. It belongs to a class of drugs known as second-generation antihistamines, which are typically non-sedating. Xyzal works by blocking a substance in the body called histamine, which is responsible for the symptoms of allergies.

Unlike older antihistamines, Xyzal has a longer duration of action, providing relief from allergy symptoms for up to 24 hours with a single daily dose. It is available in both tablet and liquid form, making it suitable for children and adults alike. Xyzal is also approved for the treatment of chronic idiopathic urticaria, a type of hives that can last for six weeks or longer without a known cause.

When taking Xyzal, it is important to follow the dosing instructions provided by your healthcare provider. Xyzal can be taken with or without food, and the tablet should be swallowed whole with a glass of water. The liquid formulation should be measured using the provided dosing cup or syringe.

As with any medication, Xyzal may cause side effects in some individuals. The most common side effects include drowsiness, dry mouth, headache, and fatigue. If you experience any severe or persistent side effects, it is important to contact your healthcare provider for further guidance.

In summary, Xyzal is an antihistamine medication that is used to treat allergy symptoms and chronic idiopathic urticaria. It provides long-lasting relief with a single daily dose and is available in both tablet and liquid form. If you are experiencing allergy symptoms, Xyzal may be an effective option for relieving your symptoms and improving your quality of life.

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Differences between Hydroxyzine and Xyzal

Hydroxyzine and Xyzal are both antihistamines used to treat allergy symptoms. While they belong to the same class of medications, they have some key differences:

Hydroxyzine Xyzal
Hydroxyzine is a first-generation antihistamine. Xyzal is a second-generation antihistamine.
Hydroxyzine can cause drowsiness and sedation. Xyzal is considered non-drowsy.
Hydroxyzine is available in both tablet and liquid forms. Xyzal is available in tablet and oral solution forms.
Hydroxyzine may be used to treat anxiety and insomnia. Xyzal is primarily used to treat allergies.
Hydroxyzine requires a prescription. Xyzal is available over-the-counter.

These differences make each medication suitable for different individuals and situations. If you are looking for a non-drowsy antihistamine specifically for allergies, Xyzal may be a better choice. However, if you need a medication that can also help with anxiety or insomnia, hydroxyzine may be more appropriate. It is important to consult with your doctor or healthcare provider to determine which medication is right for you based on your specific needs and medical history.

Differences between Hydroxyzine and Xyzal

1. Mechanism of action:

Hydroxyzine and Xyzal belong to different classes of antihistamines and have different mechanisms of action.

Hydroxyzine: It is a first-generation antihistamine that works by inhibiting the effects of histamine, a chemical produced by the body during an allergic reaction. It blocks the histamine receptors in the body, thus reducing symptoms such as itching, sneezing, and runny nose.

Xyzal: It is a second-generation antihistamine that also works by blocking histamine receptors. However, it is more selective in its action and has a longer duration of action compared to hydroxyzine.

2. Sedative effects:

Hydroxyzine is known for its sedative effects and is often used as a sedative or to treat anxiety. It can cause drowsiness and impair cognitive function, so it is usually taken at bedtime or when sedation is desired.

Xyzal, on the other hand, is considered to be non-sedating and does not typically cause drowsiness or cognitive impairment. It can be taken during the day without affecting daily activities or causing sleepiness.

3. Duration of action:

Hydroxyzine has a relatively short duration of action, usually lasting 4-6 hours. It may need to be taken multiple times a day to maintain its effectiveness.

Xyzal, on the other hand, has a longer duration of action, typically lasting 24 hours. It provides all-day relief with just one dose.

4. Availability:

Hydroxyzine is available in both prescription and over-the-counter formulations, depending on the country and specific product. It is commonly available in oral tablet, capsule, and liquid form.

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Xyzal is available as a prescription medication in most countries. It is commonly available in oral tablet and liquid form.

5. Side effects:

Common side effects of hydroxyzine include drowsiness, dry mouth, blurred vision, and dizziness. It may also cause gastrointestinal upset and headache.

Common side effects of Xyzal include headache, drowsiness, and dry mouth. It is generally well-tolerated with minimal side effects.

6. Allergies and contraindications:

Both hydroxyzine and Xyzal are contraindicated in individuals with a known hypersensitivity to the respective active ingredients or any of the other ingredients in the formulations.


Hydroxyzine and Xyzal are antihistamines with different mechanisms of action, sedative effects, duration of action, availability, and side effects. Your healthcare provider can help determine which one may be the most suitable for your specific needs and medical condition.

Benefits of Hydroxyzine

1. Allergy relief: Hydroxyzine is an antihistamine that helps relieve allergy symptoms such as sneezing, itching, watery eyes, and runny nose.

2. Itching and inflammation: Hydroxyzine can effectively reduce itching and inflammation caused by allergic reactions or skin conditions such as eczema and hives.

3. Sedation: Hydroxyzine has sedative effects and can help promote relaxation and sleep. It is sometimes used as a sleep aid for individuals with insomnia.

4. Anxiety and tension: Hydroxyzine can be used to manage symptoms of anxiety and tension. It helps reduce nervousness, restlessness, and irritability.

5. Nausea and vomiting: Hydroxyzine can be used to effectively relieve nausea and vomiting associated with motion sickness or as a result of surgery or chemotherapy.

6. Allergic reactions: Hydroxyzine can help alleviate allergic reactions, including swelling, redness, and itching caused by insect bites, poison ivy, or other irritants.

7. Pre-surgery medication: Hydroxyzine is sometimes prescribed as a pre-surgery medication to reduce anxiety and provide sedation before a surgical procedure.

8. Lower risk of dependency: Compared to other sedatives and anxiolytics, hydroxyzine has a lower risk of dependency or addiction, making it a safer choice for long-term use.

9. Wide availability: Hydroxyzine is available in various forms, including tablets, capsules, and syrups, making it convenient for individuals with different preferences or needs.

10. Minimal side effects: Hydroxyzine generally has minimal side effects, and most individuals tolerate it well. Common side effects may include drowsiness and dry mouth, which are generally mild and temporary.

Always consult with a healthcare professional before starting any medication to ensure it is suitable for your specific needs.

Benefits of Xyzal

Xyzal is a highly effective antihistamine medication that provides relief from symptoms of allergies, such as sneezing, runny nose, and itchy or watery eyes. Here are some key benefits of Xyzal:

  • 24-hour relief: Xyzal provides long-lasting relief from allergy symptoms, allowing you to go about your day without the bother of sneezing or a runny nose.
  • Fast-acting: Xyzal starts to work within an hour of taking it, providing rapid relief from allergy symptoms.
  • Non-drowsy: Unlike some other antihistamines, Xyzal does not typically cause drowsiness, so you can take it during the day without feeling sleepy.
  • Non-addictive: Xyzal is not habit-forming and can be taken as needed without the risk of dependence.
  • Easy to use: Xyzal comes in a convenient tablet form that you can take with or without food, making it simple to incorporate into your daily routine.
  • Safe for adults and children: Xyzal is approved for use in adults and children aged 6 years and older, making it a versatile option for the whole family.
  • Available over-the-counter: Xyzal is available without a prescription, so you can easily obtain it at your local pharmacy or online.
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When choosing an allergy medication, consider the benefits of Xyzal and talk to your doctor or pharmacist to see if it is the right option for you.

Which one is right for you?

Which one is right for you?

Choosing between Hydroxyzine and Xyzal can be difficult, as both medications are effective in treating allergies and itching. However, there are a few key differences that may help you make a more informed decision:


Hydroxyzine is an antihistamine that works by blocking the effects of histamine, a substance that can cause allergy symptoms. It can be used to treat allergic reactions, itching, and anxiety

Some benefits of Hydroxyzine include:

  • Fast-acting: Hydroxyzine starts working within 30 minutes to relieve itching and allergic symptoms.
  • Sedating effect: Hydroxyzine can also cause drowsiness, which may be beneficial for those experiencing difficulty sleeping due to itching or anxiety.
  • Wide availability: Hydroxyzine is available in both generic and brand-name forms, making it a cost-effective option for many.


Xyzal is also an antihistamine that works by blocking histamine and providing relief from allergy symptoms and itching.

Some benefits of Xyzal include:

  • Non-sedating: Unlike Hydroxyzine, Xyzal is less likely to cause drowsiness, making it a preferred option for those who need to remain alert and focused.
  • 24-hour relief: Xyzal provides 24-hour relief from allergy symptoms with just one daily dose, making it convenient for those with busy lifestyles.
  • Minimal side effects: Xyzal has been shown to have fewer side effects compared to other antihistamines, making it a well-tolerated option.

Ultimately, the choice between Hydroxyzine and Xyzal depends on your specific needs and preferences. If you prefer a fast-acting medication that may also help with sleep, Hydroxyzine may be the right choice for you. On the other hand, if you require a non-sedating option that provides 24-hour relief, Xyzal may be more suitable.

It is important to consult with your healthcare provider before starting any new medication to ensure it is safe and appropriate for you.